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KMID : 0363220100480020158
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Korean Journal of Dermatology
2010 Volume.48 No. 2 p.158 ~ p.160
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A Case of Mantle Cell Lymphoma with Skin Metastasis
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Ju Hye-Young
Kim Hei-Sung
Lee Jun-Young
Kim Hyung-Ok
Park Young-Min
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Abstract
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Mantle cell lymphoma is a malignant lymphoma derived from a subset of B-cells that are localized in the mantle area of the lymphoid follicle. Extranodal involvement is frequent, and especially in the bone marrow, spleen, gastrointestinal tract and Waldeyer’s ring, but skin is rarely affected. A 47-year-old male presented with a 40 day history a nodule on the abdomen on the abdomen. The histopathologic examination showed numerous atypical, small to medium sized lymphoid cells in the entire dermis. Immunohistochemically, the tumor cells were positive for CD20, CD5, CD79a and cyclin D. Our patient showed complete disappearance of his skin lesions and lymphadenopathy after combination chemotherapy. (Korean J Dermatol 2010;48(2):158∼160)
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KEYWORD
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Mantle cell lymphoma, Nodule, Skin
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